Saturday, August 23, 2008

Postdoctoral Research Fellow

Postdoctoral Research Fellow A joint research project at The Johns Hopkins University School of Medicine and the FOM-AMOLF is set up to investigate hypoxia-driven signaling pathways in breast cancer. A key component of this research is the application of novel multimodal molecular imaging techniques that combine in vivo magnetic resonance spectroscopic and optical imaging with ex vivo imaging mass spectrometric approaches.

Job description
The position will investigate hypoxia-driven signaling pathways in breast cancer cell cultures and tumor xenograft models. It will employ different molecular imaging techniques such as magnetic resonance spectroscopic imaging, optical imaging, and mass spectrometric imaging. The overall goal of this multidisciplinary project is the identification and 3D localization of novel hypoxia-driven signaling pathways in the breast tumor microenvironment. The data will be integrated within a collaborative project with the FOM-AMOLF in the laboratory of Professor Ron M. A. Heeren. The work will be carried out in a multidisciplinary team of biochemists, molecular biologists, tumor biologists, chemists, physicists, and informaticians. Progress monitoring will be carried out frequently using among others written status reports by the successful candidate.

Job Requirements
The position requires a candidate who is driven, curious, independent-thinking, and able to come up with unique solutions. This candidate should preferably be experienced or interested in the field of magnetic resonance spectroscopic and/or molecular imaging, tumor models, and cancer research. The successful candidate will have a strong affinity with technological developments and information management. Thorough knowledge of the English language is required.

Terms of Employment
The position is intended as full-time appointment in the Radiology Department of the Johns Hopkins University (JHU) School of Medicine (SOM). JHU SOM assists any new foreign employees with housing and visa applications.

The Institute
The Johns Hopkins University (JHU) School of Medicine (SOM) is one of the best in the United States, and the largest recipient of National Institutes of Health research grants to medical schools. Basic and clinical research findings made at JHU SOM have improved the health of the community and the world by setting the standard of excellence in medical education, research, and clinical care.
More information about the research at JHU SOM can be found at

The Johns Hopkins University School of Medicine In Vivo Cellular and Molecular Imaging Center (ICMIC) was established in 2003. Its mission is to identify and image key pathways specific to cancer cells that are a part of the tumor microenvironment. To achieve this goal, the JHU ICMIC combines state of the art molecular biology techniques, multimodal imaging techniques such as optical, magnetic resonance, and nuclear imaging, and unique imaging probe design. The ICMIC Program and JHU SOM offer several high-profile seminar series.

More information about the research at JHU ICMIC can be found at

AMOLF is a research institute of the Foundation for Research on Matter (FOM). It employs approximately 200 people, half of them research staff (permanent staff, postdocs and PhD-students). AMOLF is a dynamic institute with over 70 new employees coming in every year and the same number leaving to a new position in industry or university. The research program at AMOLF is interdisciplinary, with strong collaborations among the research groups. The Institute offers a wide variety of weekly work discussions and seminars. Since the institute employs many researchers from abroad, English is spoken at all work discussions and seminars.

More information about the research at AMOLF can be found at

Applications can be sent to:

Kristine Glunde, Ph.D., Assistant Professor of Radiology/Oncology
Johns Hopkins University School of Medicine
Radiology Department JHU ICMIC
212 Traylor Building
720 Rutland Avenue
Baltimore, Maryland 21205 USA

E-mail: kglunde[ at ]
Phone: (410) 614-2705
Fax: (410) 614-1948